Morphological and biochemical findings in jejunal biopsies from patients with multiple sclerosis.

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Morphological and biochemical findings in jejunal biopsies from patients with multiple sclerosis.

Gluten withdrawal from the diet is occasionally used speculatively in the management of multiple sclerosis. To assess whether there might be any rational basis for such a measure we have undertaken morphological and biochemical studies of the jejunal mucosa in 14 patients with multiple sclerosis. All were found to have morphologically normal villi, and quantitative estimation of surface-to-volu...

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Immunohistochemical findings in jejunal specimens from patients with IgA deficiency.

Jejunal biopsy specimens from 25 patients with IgA deficiency (IgAd) were studied immunohistochemically to find markers of inflammation. Five of the 25 patients had coeliac disease (CD): they were on a gluten free diet and had normal jejunal morphology. Only two of 15 specimens from control subjects had CD25+ cells in the surface epithelium, while this was seen in 19 out of 20 specimens from Ig...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1979

ISSN: 0022-3050

DOI: 10.1136/jnnp.42.5.402